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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DPYSL4
All Species:
27.27
Human Site:
Y499
Identified Species:
60
UniProt:
O14531
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14531
NP_006417.2
572
61878
Y499
H
G
V
P
R
G
L
Y
D
G
P
V
H
E
V
Chimpanzee
Pan troglodytes
XP_508117
572
61918
Y499
H
G
V
P
R
G
L
Y
D
G
P
V
H
E
V
Rhesus Macaque
Macaca mulatta
XP_001118804
950
102467
Y877
H
G
V
P
R
G
L
Y
D
G
P
V
H
E
V
Dog
Lupus familis
XP_548709
633
68509
Y560
H
G
V
P
R
G
L
Y
D
G
P
V
H
E
V
Cat
Felis silvestris
Mouse
Mus musculus
O35098
572
61943
Y499
H
G
V
P
R
G
L
Y
D
G
P
V
H
E
V
Rat
Rattus norvegicus
Q62951
564
61067
Y491
H
G
V
P
R
G
L
Y
D
G
P
V
H
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512357
612
66452
M540
M
H
A
V
P
R
G
M
Y
D
G
P
V
F
D
Chicken
Gallus gallus
Q90635
572
62312
Y499
R
G
V
P
R
G
L
Y
D
G
P
V
C
E
V
Frog
Xenopus laevis
Q640K6
571
62004
M498
L
H
A
V
P
R
G
M
Y
D
G
P
V
H
D
Zebra Danio
Brachydanio rerio
Q52PJ5
567
61525
V494
Q
L
A
I
L
K
A
V
P
R
G
M
Y
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18677
520
56275
T448
W
A
N
G
Q
L
K
T
V
Q
G
S
G
Q
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
59.1
83.5
N.A.
93.1
92.1
N.A.
65.6
76.4
71.1
67.1
N.A.
N.A.
N.A.
44.7
N.A.
Protein Similarity:
100
99.6
59.8
87.6
N.A.
96.8
95.8
N.A.
79.9
88.2
85.1
82.8
N.A.
N.A.
N.A.
61.7
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
86.6
0
0
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
86.6
0
20
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
28
0
0
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
64
19
0
0
0
10
19
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
64
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% F
% Gly:
0
64
0
10
0
64
19
0
0
64
37
0
10
0
10
% G
% His:
55
19
0
0
0
0
0
0
0
0
0
0
55
10
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% K
% Leu:
10
10
0
0
10
10
64
0
0
0
0
0
0
0
0
% L
% Met:
10
0
0
0
0
0
0
19
0
0
0
10
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
64
19
0
0
0
10
0
64
19
0
0
0
% P
% Gln:
10
0
0
0
10
0
0
0
0
10
0
0
0
10
0
% Q
% Arg:
10
0
0
0
64
19
0
0
0
10
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
64
19
0
0
0
10
10
0
0
64
19
0
64
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
64
19
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _